产品货号：
Z19973
中文名称：
LRRTM3抗体
英文名称：
Anti-LRRTM3 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-LRRTM3 Antibody |
| 指标别名 | LRRTM3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | LRRTM3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | LRRTM3 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human LRRTM3.The immunogen is located within the last 50 amino acids of LRRTM3. |
| 计算分子量 | 66kDa |
| 成分 | LRRTM3 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | LRRTM3 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation,with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation.Recent evidence suggests that LRRTM3 promotes the processing of amyloid-precursor protein (APP) by the beta-secretase BACE,leading to the proteolytic production of the Abeta42 peptide that is the main component of amyloid plaques.Furthermore,LRRTM3 maps to a region of chromosome 10 linked to both late-onset Alzheimer's disease (AD) and elevated plasma Abeta42 levels,suggesting that LRRTM3 is a functional and positional candidate gene for AD. |
| Uniprot ID | Q86VH5 |
| 基因名全称 | Leucine rich repeat transmembrane neuronal 3 |
| 蛋白名全称 | Leucine rich repeat transmembrane neuronal 3 |
| 推荐稀释比 | LRRTM3 antibody can be used for detection of LRRTM3 by Western blot at 0.5μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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